ChemicalBook > CAS DataBase List > JACOLINE

JACOLINE

Product Name
JACOLINE
CAS No.
480-76-2
Chemical Name
JACOLINE
Synonyms
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber
CB61438381
Molecular Formula
C18H27NO7
Formula Weight
369.41
MOL File
480-76-2.mol
More
Less

JACOLINE Property

Melting point:
221°C
Boiling point:
583.5±50.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
pka
12.40±0.60(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
J210403
Product name
Jacoline
Packaging
2.5mg
Price
$2640
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
1mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
2mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001950
Product name
JACOLINE
Purity
95.00%
Packaging
5MG
Price
$505.59
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
5mg
Price
$750
Updated
2021/12/16
More
Less

JACOLINE Chemical Properties,Usage,Production

Description

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

Uses

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

JACOLINE Suppliers

China 15 United Kingdom 1 United States 2 Global 18

480-76-2, JACOLINERelated Search:

retronecine 3-BUTOXYPYRROLIDINE (2S)-2,3-Dihydroxy-2-methyl-propanoic Acid Methyl Ester 90% (R)-ETHYL 3-METHYL-2-HYDROXYBUTANOATE 2,3,5,7A-TETRAHYDRO-1H-PYRROLIZINE (S)-ALLYL LACTATE JACOLINE DL-LEUCIC ACID ISOPROPYL ESTER 3-PROPOXYPYRROLIDINE

  • JACOLINE
  • Jacolin
  • [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
  • (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione
  • 480-76-2